Human Coronavirus NL63 Is Not Detected in the Respiratory Tracts of Children with Acute Kawasaki Disease
Identifieur interne : 004985 ( Main/Exploration ); précédent : 004984; suivant : 004986Human Coronavirus NL63 Is Not Detected in the Respiratory Tracts of Children with Acute Kawasaki Disease
Auteurs : Chisato Shimizu ; Hiroko Shike ; Susan C. Baker ; Francesca Garcia ; Lia Van Der Hoek ; Taco W. Kuijpers [Pays-Bas] ; Sharon L. Reed ; Anne H. Rowley ; Stanford T. Shulman ; Helen K. B. Talbot ; John V. Williams ; Jane C. Burns [États-Unis]Source :
- The Journal of Infectious Diseases [ 0022-1899 ] ; 2005.
Abstract
Kawasaki disease (KD) is a self-limited, systemic vasculitis of children for which an infectious trigger is suspected. Recently, an association between KD and human coronavirus (HCoV)–New Haven (NH) was reported, on the basis of polymerase chain reaction (PCR) with primers that also amplified HCoV-NL63. We investigated the possible association between these HCoVs in the respiratory tract and KD by reverse-transcriptase (RT) PCR and viral culture in a geographically and ethnically diverse population. Only 1 (2%) of 48 patients with acute KD was positive by RT-PCR for HCoV-NL63/NH in a nasopharyngeal swab. These data do not support an association between these HCoVs and KD
Url:
DOI: 10.1086/497170
Affiliations:
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Baker</name><affiliation><wicri:noCountry code="subField">and</wicri:noCountry></affiliation></author><author><name sortKey="Garcia, Francesca" sort="Garcia, Francesca" uniqKey="Garcia F" first="Francesca" last="Garcia">Francesca Garcia</name><affiliation><wicri:noCountry code="subField">of</wicri:noCountry></affiliation></author><author><name sortKey="Hoek, Lia Van Der" sort="Hoek, Lia Van Der" uniqKey="Hoek L" first="Lia Van Der" last="Hoek">Lia Van Der Hoek</name><affiliation><wicri:noCountry code="no comma">Department of Human Retrovirology and</wicri:noCountry></affiliation></author><author><name sortKey="Kuijpers, Taco W" sort="Kuijpers, Taco W" uniqKey="Kuijpers T" first="Taco W." last="Kuijpers">Taco W. 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Burns</name><affiliation></affiliation><affiliation wicri:level="1"><country wicri:rule="url">États-Unis</country></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">The Journal of Infectious Diseases</title><title level="j" type="abbrev">The Journal of Infectious Diseases</title><idno type="ISSN">0022-1899</idno><idno type="eISSN">1537-6613</idno><imprint><publisher>The University of Chicago Press</publisher><date type="published">2005</date><biblScope unit="vol">192</biblScope><biblScope unit="issue">10</biblScope><biblScope unit="page" from="1767">1767</biblScope><biblScope unit="page" to="1771">1771</biblScope></imprint><idno type="ISSN">0022-1899</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0022-1899</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract">Kawasaki disease (KD) is a self-limited, systemic vasculitis of children for which an infectious trigger is suspected. Recently, an association between KD and human coronavirus (HCoV)–New Haven (NH) was reported, on the basis of polymerase chain reaction (PCR) with primers that also amplified HCoV-NL63. We investigated the possible association between these HCoVs in the respiratory tract and KD by reverse-transcriptase (RT) PCR and viral culture in a geographically and ethnically diverse population. Only 1 (2%) of 48 patients with acute KD was positive by RT-PCR for HCoV-NL63/NH in a nasopharyngeal swab. These data do not support an association between these HCoVs and KD</div></front></TEI><affiliations><list><country><li>Pays-Bas</li><li>États-Unis</li></country><region><li>Hollande-Septentrionale</li></region><settlement><li>Amsterdam</li></settlement></list><tree><noCountry><name sortKey="Baker, Susan C" sort="Baker, Susan C" uniqKey="Baker S" first="Susan C." last="Baker">Susan C. 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Shulman</name><name sortKey="Talbot, Helen K B" sort="Talbot, Helen K B" uniqKey="Talbot H" first="Helen K. B." last="Talbot">Helen K. B. Talbot</name><name sortKey="Williams, John V" sort="Williams, John V" uniqKey="Williams J" first="John V." last="Williams">John V. Williams</name></noCountry><country name="Pays-Bas"><region name="Hollande-Septentrionale"><name sortKey="Kuijpers, Taco W" sort="Kuijpers, Taco W" uniqKey="Kuijpers T" first="Taco W." last="Kuijpers">Taco W. Kuijpers</name></region></country><country name="États-Unis"><noRegion><name sortKey="Burns, Jane C" sort="Burns, Jane C" uniqKey="Burns J" first="Jane C." last="Burns">Jane C. Burns</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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